Handbook of Abiogenetic Counseling Affectionate Serum Amateur Awning
18 June 06:08
Affectionate Serum Amateur Screen
*Offer ultrasound -
*confirm gestational age (MSAFP increases throughout this time in abundance and the g.a. may just be underestimated)
*rule out anencephaly, ONTD, fetal demise, assorted gestation
*If annihilation is begin on ultrasound and dates are correct
*2.0-2.9 MoM, g.a. <18 wks echo serum AFP
*>3 MoM, or g.a. > 18 wks action amnio (measures AFP 90-96% authentic and can aswell admeasurement Acetylcholinesterase akin which detects 99% of ONTD) aswell detects chromosomal abnormalities
*If the couldcause of the acclivity is still not articular and AFP was greater than 3.0 MoM, consecutive ultrasounds and antenatal testing should be advised (watch for pre-eclampsia)
*Offer ultrasound
*Confirm gestational age - off by >10 canicule alarm and get a recalculation (uE3 alotof important increases with gestational age)
*Explain what they attending for that ability accommodate clues as to whether the fetus is afflicted (not analytic admitting so it cannot acquaint us for abiding whether or not the fetus has trisomy 18)
*Offer amniocentesis
*diagnostic testing that will accurately actuate if the fetus has trisomy 18 with greater than 99% accuracy
*risks of abortion 0.5 % aloft baseline
*also detects assorted additional chromosomal abnormalities
*If hCG is <2.5 MoM and couldcause is not identified, a third trimester ultrasound for advance should be advised and accommodating monitored for pre-eclampsia
*Offer ultrasound
*Confirm gestational age
*if off by 10 canicule or added and fatigued afore 15 weeks than echo at 15-18 wks
*if off by 10 canicule of added and fatigued at or afterwards 15 wks than recalculate the DS accident using adapted age
*Explain additional things they will attending for on the ultrasound that may be signs of Down syndrome
*Signs are begin on ultrasound in about 2/3 of fetuses with Down syndrome
*Whether or not signs are begin ultrasound cannot affirm for assertive whether or not the fetus is affected.
*Offer amniocentesis (diagnostic testing that will acquaint us whether the fetus has Down affection with >99% accurateness and aswell detects additional chromosomal abnormalities
*If hCG is <2.5 MoM and couldcause is not identified, a third trimester ultrasound for advance should be advised and accommodating monitored for pre-eclampsia
*Focus on their results
*These statistics are for the citizenry and dont absolutely affect their results
*They may be abashed about this admitting so abode it if there are questions
*Detection rate
*Given the fetus is afflicted apprehension amount is the adventitious that it will be best up and accept a absolute screen.
*NOT ALL Afflicted FETUSES ARE Best UP ON Amateur SCREEN
*False positive
*Chance of accepting an artless fetus and accepting a absolute awning out of all artless pregnancies
*Since there are added artless pregnancies than afflicted pregnancies it may assume like there is a ample complete # of false positives
*If their fetus is artless it doesnt meant that the amateur awning was amiss because all it is declared to do is aces out women at added accident for NTDs, Down syndrome, and trisomy 18.
*85% apprehension amount - agency that out of 100 pregnancies area the fetus has an ONTD 85 of them are best up by this screening (it does not aces up bankrupt neural tube defects)
*80% of cases of accessible spina bifida
*90% of cases of anencephaly
*60-80% apprehension amount - agency that out of 100 pregnancies area the fetus has trisomy 18, 60 or 80 of them will be best up as a absolute screen
*.5% false absolute amount - agency that out of 200 women who are accustomed a fetus after trisomy 18 1 of those 200 would accept a absolute screen
*60-65% apprehension amount - agency that out of 100 pregnancies area the fetus has Down affection about 65 will be best out by this screening
*5% false absolute amount - agency that out of 100 women that do not accept a adolescent with Down affection 5 of them will accept a absolute screen
*85-90% apprehension rate
*25% false absolute rate
*Assess if there are any questions or if there is annihilation that she would like me to explain again
*Assess how she feels about added testing options
*Check for compassionate by accepting her explain how she feels about her risk
*Lecture by Sharon K. Trumpy, M.S. Affectionate Serum Amateur Brand Screening. 02/06/02.
*Bianchi, D.W., Crombleholme T.M., Dalton, M.E. Fetology: Analysis & Administration of the Fetal Patient. McGraw Hill, New York, 2000.
*Mulinsky, A (ed). 1998. Abiogenetic Disorders and the Fetus: Diagnosis, Blockage and Treatment.
*http://www.questdiagnostics.com/patient/womenshealth/maternal_serum_screen.html
*http://epregnancy.com/info/prenataltests/test-afp.htm
*http://www.smartmoms.org/prenatal-tests/test6.html#who%20tested
The advice in this outline was endure adapted in 2002.
*Offer ultrasound -
*confirm gestational age (MSAFP increases throughout this time in abundance and the g.a. may just be underestimated)
*rule out anencephaly, ONTD, fetal demise, assorted gestation
*If annihilation is begin on ultrasound and dates are correct
*2.0-2.9 MoM, g.a. <18 wks echo serum AFP
*>3 MoM, or g.a. > 18 wks action amnio (measures AFP 90-96% authentic and can aswell admeasurement Acetylcholinesterase akin which detects 99% of ONTD) aswell detects chromosomal abnormalities
*If the couldcause of the acclivity is still not articular and AFP was greater than 3.0 MoM, consecutive ultrasounds and antenatal testing should be advised (watch for pre-eclampsia)
*Offer ultrasound
*Confirm gestational age - off by >10 canicule alarm and get a recalculation (uE3 alotof important increases with gestational age)
*Explain what they attending for that ability accommodate clues as to whether the fetus is afflicted (not analytic admitting so it cannot acquaint us for abiding whether or not the fetus has trisomy 18)
*Offer amniocentesis
*diagnostic testing that will accurately actuate if the fetus has trisomy 18 with greater than 99% accuracy
*risks of abortion 0.5 % aloft baseline
*also detects assorted additional chromosomal abnormalities
*If hCG is <2.5 MoM and couldcause is not identified, a third trimester ultrasound for advance should be advised and accommodating monitored for pre-eclampsia
*Offer ultrasound
*Confirm gestational age
*if off by 10 canicule or added and fatigued afore 15 weeks than echo at 15-18 wks
*if off by 10 canicule of added and fatigued at or afterwards 15 wks than recalculate the DS accident using adapted age
*Explain additional things they will attending for on the ultrasound that may be signs of Down syndrome
*Signs are begin on ultrasound in about 2/3 of fetuses with Down syndrome
*Whether or not signs are begin ultrasound cannot affirm for assertive whether or not the fetus is affected.
*Offer amniocentesis (diagnostic testing that will acquaint us whether the fetus has Down affection with >99% accurateness and aswell detects additional chromosomal abnormalities
*If hCG is <2.5 MoM and couldcause is not identified, a third trimester ultrasound for advance should be advised and accommodating monitored for pre-eclampsia
*Focus on their results
*These statistics are for the citizenry and dont absolutely affect their results
*They may be abashed about this admitting so abode it if there are questions
*Detection rate
*Given the fetus is afflicted apprehension amount is the adventitious that it will be best up and accept a absolute screen.
*NOT ALL Afflicted FETUSES ARE Best UP ON Amateur SCREEN
*False positive
*Chance of accepting an artless fetus and accepting a absolute awning out of all artless pregnancies
*Since there are added artless pregnancies than afflicted pregnancies it may assume like there is a ample complete # of false positives
*If their fetus is artless it doesnt meant that the amateur awning was amiss because all it is declared to do is aces out women at added accident for NTDs, Down syndrome, and trisomy 18.
*85% apprehension amount - agency that out of 100 pregnancies area the fetus has an ONTD 85 of them are best up by this screening (it does not aces up bankrupt neural tube defects)
*80% of cases of accessible spina bifida
*90% of cases of anencephaly
*60-80% apprehension amount - agency that out of 100 pregnancies area the fetus has trisomy 18, 60 or 80 of them will be best up as a absolute screen
*.5% false absolute amount - agency that out of 200 women who are accustomed a fetus after trisomy 18 1 of those 200 would accept a absolute screen
*60-65% apprehension amount - agency that out of 100 pregnancies area the fetus has Down affection about 65 will be best out by this screening
*5% false absolute amount - agency that out of 100 women that do not accept a adolescent with Down affection 5 of them will accept a absolute screen
*85-90% apprehension rate
*25% false absolute rate
*Assess if there are any questions or if there is annihilation that she would like me to explain again
*Assess how she feels about added testing options
*Check for compassionate by accepting her explain how she feels about her risk
*Lecture by Sharon K. Trumpy, M.S. Affectionate Serum Amateur Brand Screening. 02/06/02.
*Bianchi, D.W., Crombleholme T.M., Dalton, M.E. Fetology: Analysis & Administration of the Fetal Patient. McGraw Hill, New York, 2000.
*Mulinsky, A (ed). 1998. Abiogenetic Disorders and the Fetus: Diagnosis, Blockage and Treatment.
*http://www.questdiagnostics.com/patient/womenshealth/maternal_serum_screen.html
*http://epregnancy.com/info/prenataltests/test-afp.htm
*http://www.smartmoms.org/prenatal-tests/test6.html#who%20tested
The advice in this outline was endure adapted in 2002.
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Tags: counseling, screen, gestational detects, chromosomal, fetus, abnormalities*if, gestational, serum, triple, maternal, , chromosomal abnormalities*if, gestational age, serum triple, maternal serum, maternal serum triple, serum triple screen, counseling maternal serum, genetic counseling maternal, |
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